CME Information

LEARNING OBJECTIVES
Upon completion of the activity, participants should be able to:

• Describe the underlying genetic etiology and general characteristics of the LSDs
• Identify causes of mis- and delayed diagnosis of LSDs
• List the therapeutic options for managing LSDs

ACTIVITY FACULTY
Jennifer Gannon, MD
Clinical Biochemical Geneticist
Clinical Assistant Professor of Pediatrics
University of Missouri-Kansas City School of Medicine

Rachel E. Hickey, MS, LCGC
Genetic Counselor
Ann & Robert H. Lurie Children’s Hospital of Chicago

Meghan Strenk, MS, GCG
Senior Genetic Counselor
Clinical Genetics
Children’s Mercy Kansas City

TARGET AUDIENCE
This activity is intended for genetic counselors, physicians, and other members of the healthcare team.

STATEMENT OF NEED
Given the large number of lysosomal storage disorders (LSDs), it is unlikely that an individual disorder can be recognized immediately upon presentation, thereby delaying a critical diagnosis. It is critical that genetic counselors, physicians, and other members of the healthcare team become conversant with the LSDs in general and the clinical challenges and implications associated with them so that they can contribute to earlier identification and intervention in an incurable, but manageable disease if identified in a timely fashion. This need is particularly underscored given that almost 60% of genetic counselors are involved with direct patient care.

ACCREDITATION STATEMENT
The France Foundation is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

CREDIT DESIGNATION
This activity is provided by The France Foundation in collaboration with the National Society of Genetic Counselors.

Genetic Counselors: The National Society of Genetic Counselors (NSGC) has authorized The France Foundation to offer up to 0.1 CEUs or 1 Category 1 contact hours for the activity Understanding Lysosomal Storage Disorders. The American Board of Genetic Counseling (ABGC) will accept CEUs earned at this program for the purposes of genetic counselor certification and recertification.

Physicians: The France Foundation designates this enduring activity for a maximum of 1.0 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Nurses: Nurses who are certified by the American Nurses Credentialing Center (ANCC) may utilize activities that are certified by ACCME-accredited providers toward their requirement for certification renewal by the ANCC. A certificate of attendance will be provided by The France Foundation, an ACCME accredited provider.

DISCLOSURE POLICY
In accordance with the ACCME Standards for Commercial Support The France Foundation (TFF) and the National Society of Genetic Counselors (NSGC) require that individuals in a position to control the content of an educational activity disclose all relevant financial relationships with any commercial interest. TFF and NSGC resolve all conflicts of interest to ensure independence, objectivity, balance, and scientific rigor in all their educational programs. Furthermore, TFF and NSGC seek to verify that all scientific research referred to, reported, or used in a CME/CE activity conforms to the generally accepted standards of experimental design, data collection, and analysis. TFF and NSGC are committed to providing learners with high-quality CME/CE activities that promote improvements in health care and not those of a commercial interest.

Activity Staff Disclosures
The planners, reviewers, editors, staff, CME committee, or other members at The France Foundation who control content have no relevant financial relationships to disclose.

The planners, reviewers, editors, staff, CE committee, or other members at the National Society of Genetic Counselors who control content have no relevant financial relationships to disclose.

Planning Committee & Faculty Disclosures

The planning committee member and faculty listed below report that they have no relevant financial relationships to disclose:

• Jennifer Gannon, MD, FAAP, FACMG

The following planning committee member and faculty report that they have relevant financial relationships to disclose:

• Rachel Hickey, MS, CGC is a member of the Speaker’s Bureau for Takeda.
• Meghan Strenk, MS, CGC is a member of the Speaker’s Bureau for Genzyme.

DISCLOSURE OF UNLABELED USE
TFF and NSGC require CME faculty (speakers) to disclose when products or procedures being discussed are off label, unlabeled, experimental, and/or investigational, and any limitations on the information that is presented, such as data that are preliminary, or that represent ongoing research, interim analyses, and/or unsupported opinion. Faculty in this activity may discuss information about pharmaceutical agents that is outside of US Food and Drug Administration approved labeling. This information is intended solely for continuing medical education and is not intended to promote off-label use of these medications. TFF and NSGC do not recommend the use of any agent outside of the labeled indications. If you have questions, contact the Medical Affairs Department of the manufacturer for the most recent prescribing information.

COMMERCIAL SUPPORT ACKNOWLEDGMENT
This activity is supported by an educational grant from Sanofi Genzyme.

DISCLAIMER
The France Foundation and the National Society of Genetic Counselors present this information for educational purposes only. The content is provided solely by faculty who have been selected because of recognized expertise in their field. Participants have the professional responsibility to ensure that products are prescribed and used appropriately on the basis of their own clinical judgment and accepted standards of care. The France Foundation, the National Society of Genetic Counselors, and the commercial supporter(s) assume no liability for the information herein.

COPYRIGHT INFORMATION
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• The materials are to be used solely for personal, noncommercial, informational and educational purposes. The materials are not to be modified. They are to be distributed in the format provided with the source clearly identified. The copyright information or other proprietary notices may not be removed, changed, or altered.
• Materials may not be published, uploaded, posted, transmitted (other than as set forth herein), without The France Foundation's prior written permission.

PRIVACY POLICY
The France Foundation protects the privacy of personal and other information regarding participants and educational collaborators. The France Foundation will not release personally identifiable information to a third party without the individual's consent, except such information as is required for reporting purposes to the ACCME.

The France Foundation maintains physical, electronic, and procedural safeguards that comply with federal regulations to protect against the loss, misuse or alteration of information that we have collected from you.

Additional information regarding The France Foundation's Privacy Policy can be viewed at http://www.francefoundation.com/privacy-policy.

CONTACT INFORMATION
If you have questions about this CME activity, please contact The France Foundation at 860-434-1650 or info@francefoundation.com.